Antiemetics for Chemotherapy-Induced Nausea and Vomiting Occurring Despite Prophylactic Antiemetic Therapy
نویسندگان
چکیده
منابع مشابه
Chemotherapy-induced nausea and vomiting: which antiemetic for which therapy?
Chemotherapy-induced nausea and vomiting (CINV) remains an important and common toxicity of cancer treatment. Recent guideline revisions have classified chemotherapeutic agents into four categories of emesis risk without the use of preventive agents: high (> 90%), moderate (30%--90%), low (10%-30%), and minimal (< 10%). Currently available antiemetic agents, including corticosteroids, 5-hydroxy...
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Chemotherapy-induced nausea and vomiting (CINV) is one of the most common symptoms feared by patients, but may be prevented or lessened with appropriate medications. Several antiemetic options exist to manage CINV. Corticosteroids, serotonin receptor antagonists, and neurokinin receptor antagonists are the classes most commonly used in the prevention of CINV. There are many alternative drug cla...
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Chemotherapy-induced nausea and vomiting (chemotherapyinduced emesis) is a common treatment-related side effect that has a detrimental effect on the quality of life of patients with cancer and may lead to dose reductions in or discontinuation of chemotherapy. The development of new antiemetic agents has dramatically changed the landscape of chemotherapy-induced emesis. In the 1970s, prolonged h...
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Chemotherapy induced nausea and vomiting (CINV) are two of the most feared adverse events experienced by cancer patients undergoing chemotherapy. Metoclopramide was derived from procainamide in the 1950s and one of the first drugs investigated in the prophylaxis of nausea and vomiting induced by chemotherapy. The breakthrough came in 1981 with the recognition that high-dose metoclopramide was e...
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Since the 1990s, new antiemetic agents have significantly reduced the incidence of nausea and vomiting associated with chemotherapy. Specifically, these agents are the serotonin receptor antagonists and consist of dolasetron (Anzamet, Aventis Pharmaceuticals, Bridgewater, NJ), granisetron (Kytril, Roche Pharmaceuticals, Nutley, NJ), ondansetron (Zofran, GlaxoSmithKline, Research Triangle Park, ...
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ژورنال
عنوان ژورنال: Journal of Palliative Medicine
سال: 2011
ISSN: 1096-6218,1557-7740
DOI: 10.1089/jpm.2011.0058